In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

نویسندگان

  • Moritz Nazarenus
  • Qian Zhang
  • Mahmoud G Soliman
  • Pablo del Pino
  • Beatriz Pelaz
  • Susana Carregal-Romero
  • Joanna Rejman
  • Barbara Rothen-Rutishauser
  • Martin J D Clift
  • Reinhard Zellner
  • G Ulrich Nienhaus
  • James B Delehanty
  • Igor L Medintz
  • Wolfgang J Parak
چکیده

The interfacing of colloidal nanoparticles with mammalian cells is now well into its second decade. In this review our goal is to highlight the more generally accepted concepts that we have gleaned from nearly twenty years of research. While details of these complex interactions strongly depend, amongst others, upon the specific properties of the nanoparticles used, the cell type, and their environmental conditions, a number of fundamental principles exist, which are outlined in this review.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2014